CBD and Gut health
It is clear to all of us that our heart pumps blood, oxygen circulates in the lungs and the immune system protects the body from harmful invaders. You may also know that the purpose of the digestive system is to distribute food so that valuables are taken in but unnecessarily excreted.
Thanks to advances in technology and research, we understand today that the function of digestion is much more complex than we thought. The microbial composition of the digestive system significantly affects our overall health and emotional well-being.
Understanding the essential connection between the gut and the brain will also help assess the therapeutic potential of CBD.
CBD oil and the gut’s microbiome.
The bacterial profile of the intestinal microbiome is as unique as the fingerprint. Although the growing popularity of probiotics provides a better understanding of digestive health, relatively few people understand how the composition of bacteria in their gut affects many functions throughout the body.
Studies show that using a variety of beneficial gut bacteria, it prevents intestinal inflammation, strengthens the immune system and regulates mood and emotions by producing essential neurotransmitters, including serotonin, dopamine and gamma-aminobutyric acid (GABA). The neurotransmitters that microbes produce in your gut are needed for communication between your digestive tract and the brain.
Current research suggests a strong connection between imbalances in the microbial composition of the gut and numerous health conditions, including food allergies, depression, obesity, chronic inflammation, and tumors.
Cannabinoids such as cannabidiol (CBD) and tetrahydrocannabinol (THC) are being studied for their effects on intestinal microbiome health. In a 2019 study, rats with neuro infection were given a combination of CBD and THC. The researchers wanted to see if cannabinoids would affect neuroinflammation due to their effects on the rat gut microbiome.
The researchers found that the CBD-THC mixture reduced the amount of Akkermansia muciniphila (A. muc) in the gut, causing a reduction in neuroinflammation. The study concludes: “Overall, our data suggest that cannabinoids may… suppress neuroinflammation by promoting a healthy gut microbiota.”
More research is needed, but this is already is a promising start.
The gut’s endocannabinoid system.
The gut maintains constant contact with the central nervous system to regulate the production of neurotransmitters, protect the gut, regulate motility and more. The efficient functioning of important systems in the body depends on the constant interaction with the endocannabinoid system, which is the largest regulatory system in our body. The endocannabinoid system (ECS) depends on the production of messengers (neurotransmitters) to interact with the corresponding endocannabinoid receptors.
Endocannabinoid messengers are called cannabinoids. The two main cannabinoids synthesized in the body are the endocannabinoids anandamide and 2-Ag (2-arachidonoylglycerol). These important messengers regulate the communication between the intestines and the brain. Endocannabinoids are produced as needed and are rapidly broken down by metabolic enzymes.
Ideally, the body produces enough endocannabinoids to make important processes work more efficiently. Unfortunately, this doesn’t always work. As a result of stress, illness or injury, the body may need more cannabinoids than it can produce.
When the body does not create enough messengers in the endocannabinoid system to interact with the receptors, communication is lost. Because the endocannabinoid system regulates almost all essential functions in our body, many researchers today believe that endocannabinoid deficiency causes various diseases.
Fortunately, the body responds to the cannabinoids found in cannabis plants. CBD (cannabidiol) is just one of more than 100 phytocannabinoids found in the Cannabis plant. CBD imitates the effects of endocannabinoids produced in the body, interacts with ECS receptors and helps support important functions that are regulated by the endocannabinoid system, including the gut.
CBD oil for gastrointestinal issues.
The growing popularity of CBD products is probably related to the way it helps regulate so many important functions in our body. Studies show that CBD has anxiolytic, anti-inflammatory, analgesic, anti-nausea and antispasmodic properties. This means that CBD can prevent inflammation, nausea, chronic pain and stress reactions that cause damage to the gastrointestinal tract and other gastrointestinal health.
Ulcerative colitis is an inflammatory bowel disease, one of several disorders of the gastrointestinal tract caused by an overly aggressive immune system response to the gut biome. Ulcerative colitis is thought to be caused by an imbalance between the intestinal microbiota and mucosal immunity, leading to excessive intestinal inflammation. Symptoms of the disorder may include abdominal pain and cramps, diarrhea (with pus or blood), rectal bleeding, weight loss and fatigue.
Animal studies have shown that CBD reduces intestinal inflammation by inhibiting the production of proinflammatory cytokines. In other words, CBD has shown to stop inflammation in the gut before it even begins. Similar results were seen by researchers looking at colon samples from ulcerative colitis patients taking CBD oil.
Leaky gut syndrome.
One of the most important functions of the intestinal biomass is the protection of the gastrointestinal mucosa. When the delicate balance of the intestinal microbiota is disturbed, harmful bacteria multiply. The imbalance between beneficial and harmful bacteria causes inflammation that increases intestinal permeability. Increased intestinal permeability allows harmful bacteria to pass through your intestines and migrate to other areas of the body. Some researchers believe that leaky gut syndrome can cause other types of inflammatory bowel disease.
Symptoms of leaky gut syndrome include chronic diarrhea or constipation, fatigue, headache, widespread inflammation, joint pain, and skin problems such as rash, pimples, or eczema. Current research shows that CBD oil helps to restore healthy intestinal barrier function, protects the digestive mucosa from damage and restores the integrity of the intestinal mucosa.
Irritable Bowel Syndrome.
Irritable bowel syndrome is a fairly common indigestion that affects the colon. Those living with irritable bowel syndrome are likely to experience gas, bloating, abdominal pain, constipation, diarrhea, or both. Although the exact causes are still unclear, the main causes are now thought to be stronger than average gastrointestinal muscle contractions, poorly coordinated signaling between the brain and intestines, and changes in the intestinal flora. Symptoms can be caused by certain foods, hormonal fluctuations or stress.
The famous cannabinoid researcher Dr. Ethan Russo considers irritable bowel syndrome to be one of the many chronic health conditions caused by endocannabinoid deficiency. Although very few clinical studies have been performed to confirm the benefits of CBD oil, we know that gastrointestinal secretion, pathogen, and inflammation are involved in processes regulated by the ECS.
Studies show that people with irritable bowel syndrome have elevated TRPV1 nerve fibers, which are thought to contribute to GI hypersensitivity. CBD has shown to increase anandamide production while inhibiting enzymes that degrade it, which ultimately desensitizes TRVP1 nerve fibers.
Crohn’s disease is an autoimmune disease that causes the immune system to erroneously target beneficial gut bacteria while allowing unhealthy bacteria to thrive. The resulting chronic inflammation causes intestinal trauma and ulcers.
Symptoms of Crohn’s disease may include abdominal cramps, fever, fatigue, weight loss and bloody stools. Complications may include intestinal wall abscesses, cracks, and nutrient malabsorption.
A 2018 study confirms the therapeutic potential of cannabinoids (CBD and THC) in the symptoms of Crohn’s disease. Study participants who received CBD oil reported an improvement in quality of life and a significant reduction in Crohn’s symptoms, with strict remission criteria in 65% of cases. Surprisingly, the researchers did not find significant improvements in inflammatory markers but noted that CBD improved symptoms in a significant number of test subjects.
Weight gain and obesity.
Although many people do not believe that obesity is the result of indigestion, your ability to maintain weight and manage eternal hunger may be more dependent on intestinal health than you think. Evidence shows that the composition of bacteria in the gut has a direct effect on how the body burns calories, absorbs nutrients and stimulates the desire to eat.
To help control weight and appetite, intestinal bacteria break down previously undigested carbohydrates (polysaccharides) into short-chain fatty acids. When fat cells discover short-chain fatty acids, they release a hormone called leptin to signal to your brain that you are full. If an unhealthy intestinal biome inhibits the excretion of short-chain fatty acids, the urge to eat will continue. The feeling of satisfaction about the meal will depend on which bacteria win the fight.
Studies show that cannabinoid receptors are directly involved in regulating food intake, caloric intake, hormone secretion and fat accumulation. Stimulation of specific endocannabinoid receptors has shown to reduce food intake and increase fat metabolism. Supporting the functions of your endocannabinoid system could help you feel satisfied with less food while supporting healthy digestive processes.
Studies have shown that CBD oil can improve overall bowel health:
– reducing inflammation. Deterioration of intestinal health is often associated with chronic inflammation in the body, and clinical studies have shown that CBD can temporarily reduce this inflammation, as well as reduce bloating and stomach pain. The first way CBD helps improve bowel health is to reduce the inflammation associated with it.
– improving intestinal permeability. Inflammation is a major cause of intestinal permeability, CBD is already helping to alleviate this particular problem. In addition, in a study with rats, the researchers found that cannabinoids are likely to increase intestinal motility and possibly decrease intestinal permeability (…), especially in diabetic patients’. More research suggests that CBD appears to increase the amount of gut bacteria while reducing and destroying all bad bacteria and pathogens, again helping to reduce the “passage” of the gut.
– reducing anxiety and stress also improves bowel health. We know that stress and anxiety play a devastating role in intestinal health. It has even been shown that the endocannabinoid system appears to be affected by early life stress, which can later turn into serious health problems, meaning that an underactive endocannabinoid system can actually cause intestinal problems. The use of CBD to reduce stress is ancient and well known. Indeed, many studies have shown the ability of CBD to promote resistance to stress and reduce anxiety by relaxing the body’s muscles.
– reducing pain. Of all the uses of CBD, it seems to be the main reason for its use, and dozens of randomized controlled trials with thousands of patients have positively demonstrated its ability to reduce pain in all types of disorders. This, of course, makes sense because the endocannabinoid system is centrally involved in the processing of pain signals. Therefore, by activating this system using phytocannabinoids such as CBD, we can effectively reduce pain, both by relaxing the muscles that respond to it and by actually treating the cause of the pain.
CBD is a universal tool for intestinal health.
By improving these four factors (inflammation, bowel permeability, stress, and pain), we can effectively reduce both the symptoms of poor bowel health, such as diarrhea, bloating, and pain, and promote overall bowel health.
How to use CBD oil for gut health?
Many people use CBD oil for gut health, but CBD is not perfect for everyone. If you are receiving treatment for a medical condition or take medication, it’s important to discuss CBD use with your doctor before starting treatment. CBD can interact with a significant number of medications, so you will want to be sure that you have made the safest decision for your health.
If your doctor says you can try CBD oil, you will need to decide which type(s) of CBD product you want to use. These product explanations could be useful for first-time CBD users.
For a while, we haven’t looked at CBD product types or admission methods on our blogs, so let’s sketch a little reminder again. Let’s take a look at all kinds, including those that may not be available in your market at all.
CBD oil drops or tinctures.
CBD tinctures include CBD distilled with alcohol and are often soluble in water for optimal bioavailability and absorption. CBD oil drops are a mixture of Cannabis extract and carrier. Many companies use MCT oil (medium-chain triglycerides) to promote the absorption of cannabinoids and provide additional health benefits. GWEE PRODUCTS uses high-quality olive oil, which in itself has a good effect on the body as a whole.
Although CBD tinctures can be mixed with food or added to a favorite beverage, many people prefer sublingual (sublingual) use of CBD oil drops.
CBD vape products.
Cannabinoids can also be inhaled in the same way as smoking, choosing disposable vape pens, refilled vape cartridges with CBD vape oil to be used with your favorite vape tool. Vaping CBD is considered to be the most effective CBD intake method because cannabinoids bypass your digestive system. Although CBD vaping provides fast results, the effects are not as long-lasting as other CBD products, and they usually last up to 1 hour. This method is used when you need to quickly reduce bad feelings or seizures.
CBD suppositories offer significant benefits for intestinal health compared to other intake methods, as rectal absorption provides the best bioavailability of cannabinoids. The effects of CBD suppositories are usually felt within 10-15 minutes of insertion and may last for 6 to 8 hours. Suppositories may be your best option if you have difficulty swallowing, nausea, stomach pain or other digestive problems.
CBD capsules and edibles.
CBD capsules, soft gels, and other foods such as CBD gummies are preferred by CBD users who want a consistent dose of CBD in a convenient form. Capsules and rubber candies are easy to remove and you should not be afraid to mix, measure or count drops.
Because the capsules and gummies have to go through your digestive system, you may not feel the effects for up to an hour. But on exposure, their effects last for 4 to 6 hours, depending on the dose and metabolism of each organism.
You don’t even have to have a serious indigestion to live with the symptoms of an unhealthy gut. Because many neurotransmitters located in the body are synthesized in the digestive tract, an unhealthy intestinal biome can affect everything from mood, energy levels, pain levels, or skin health.
Of course, restoring bowel health should be a holistic practice that includes other elements such as probiotics, meditation and the use of healthy natural foods. However, it seems that CBD could potentially be a new strong arsenal in reducing our intestinal diseases.
If you are interested in supporting healthy bowel function with CBD oil, be sure to buy it from a reputable source. Your CBD experience is directly affected by the quality and purity of the products you choose.
The information on the internet about CBD products and their use will be ambiguous, so we always recommend reading safe and reliable sources. We also use websites related to the Cannabis industry, research and education to prepare information.
The content of this site is for informational purposes only. We are not medical experts and this should not be interpreted as medical advice. Be sure to consult your doctor before undergoing CBD or other treatment.
The chemistry of every human body and brain is unique, so the use of CBD to improve mental as well as physical health does not guarantee results. However, many GWEEPRODUCTS CBD oil users have included it into their daily routine as one of the therapies for improving mental, physical health and quality of life.
References: cbdoilreview.org; ncbi.nlm.nih.gov; projectcbd.org